Purine nucleosides
Cayman Chemical 2-Fluoro-2-deoxyadenosIn 1g
A prodrug form of 2-F-adenine; reduces mean tumor weight in an E. coli purine nucleoside phosphorylase-expressing D54 glioblastoma mouse xenograft model at 100 mg/kg
Cambridge Isotope Laboratories 2-Deoxyguanosine H2O (13C10 98% 15N5 96-98%) 25 mg
2-Deoxyguanosine H2O (13C10 98% 15N5 96-98%) 25 mg
Genscript Corporation CA15-3 AntibodyA5D8 mAb Mo
CA15-3 (Carcinoma antigen 15-3) is also known as MUC 1 antigen It is a membrane-anchored mucin-type glycoprotein present in malignant cells It is used as tumor marker to monitor breast cancer treatment and disease recurrence
Medchemexpress LLC 2'-Deoxyadenosine-5'-triphosphate-15N5, dilithium | 99.3% | 508.01 | 1 MG
This product is 2'-Deoxyadenosine-5'-triphosphate-15N5, dilithium, a chemical compound with a molecular weight of 508.01. It is supplied as a colorless to light yellow liquid solution and has a purity of 99.3%. This compound is intended for research use only.
- High purity of 99.3%
- Isotopic enrichment of 98.7%
- Available as a colorless to light yellow liquid
- Store at -20°C for up to 2 years
- Molecular formula C10H14Li215N5O12P3
Apexbio Technology LLC 2'-Deoxyguanosine 961-07-9 1g
2 -Deoxyguanosine (CAS 961-07-9) is a purine deoxyribonucleoside comprising guanine coupled to a deoxyribose moiety As an essential constituent of DNA it serves as a substrate in multiple nucleotide metabolism pathways Its interconversion with 2 -deoxyguanosine 5 -monophosphate is mediated by purine 5 -nucleotidase and deoxyguanosine kinase reflecting its role in nucleic acid turnover In biomedical research 2 -deoxyguanosine is utilized to study DNA synthesis repair mechanisms and enzymatic processes involving nucleoside metabolism Altered deoxyguanosine homeostasis has been implicated in purine nucleoside phosphorylase deficiency underscoring its significance in inherited metabolic disorders
Medchemexpress LLC 2-Deoxyadenosine 5 10mM 1mL
2 -Deoxyadenosine 5 -monophosphate disodium a nucleic acid AMP derivative is a deoxyribonucleotide found in DNA 2 -Deoxyadenosine 5 -monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[1]
Biotium MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker)(VU-4H5), CF740 conjugate, 0.1mg/mL
MAb VU-4H5 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of MAb VU4H5 is APDTR as established with 'epitope fingerprinting'. VU-4H5 preferentially binds to under-glycosylated 'tumor' MUC1. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | 267.25 | 1 G
2'-Deoxyguanosine is a purine nucleoside with a variety of biological activities. It can induce DNA division in mouse thymus cells and is a potent cell division inhibitor in plant cells. In vitro, it inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively.
- Classified as an endogenous metabolite related to cancer
- Analytical standard intended for research and analytical applications (for standard version HY-17563R)
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MM * 1 ML
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.
- Nucleoside analogue
- Can be incorporated into de novo-synthesized telomeres by telomerase
- Rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM (in vitro)
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies, superior to that observed with 6-thioguanine treatment (in vivo)
- Increases telomere dysfunction in tumor cells in vivo
- Appearance: Solid
- Color: White to yellow
Medchemexpress LLC Deoxyguanosine triphosphate trisodium solution | 93919-41-6 | 99.95% | 573.13 | 57.31 MG
Deoxyguanosine triphosphate (dGTP) trisodium solution (100mM) is a nucleotide precursor in cells for DNA synthesis. It is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
- Nucleotide precursor for DNA synthesis.
- Used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.
- High purity: 99.95%.
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | >99.9% | 267.25 | 5 G
2'-Deoxyguanosine is a purine nucleoside with diverse biological activities. It can induce DNA division in mouse thymus cells and acts as a potent cell division inhibitor in plant cells. It inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively. This product is intended for research use only.
- Induces DNA division in mouse thymus cells.
- Acts as a potent cell division inhibitor in plant cells.
- Inhibits clonal growth of HL-60 and K562 leukemia cells.
- Intended for research applications.
2'-Deoxyadenosine Monohydrate, Thermo Scientific™
CAS: 16373-93-6 Molecular Formula: C10H13N5O3 Molecular Weight (g/mol): 251.25 MDL Number: MFCD00149364 InChI Key: OLXZPDWKRNYJJZ-YUZWJPFSNA-N Synonym: 2'-deoxyadenosine monohydrate,2r,3s,5r-5-6-amino-9h-purin-9-yl-2-hydroxymethyl tetrahydrofuran-3-ol hydrate,adenosine, 2'-deoxy-, monohydrate,2'-deoxyadenosine hydrate,2-deoxyadenosine hydrate,deoxyadenosine hydrate,9-2-deoxy-,a-d-ribofuranosyl adenine,deoxyadenosine monohydrate,2-deoxyadenosine monohydrate,2?-deoxyadenosine monohydrate PubChem CID: 9549172 IUPAC Name: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol SMILES: NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC=N1
MP Biomedicals, Inc 2'-Deoxyguanosine, 99 to 100%, MP Biomedicals™
CAS: 961-07-9 Molecular Formula: C10H13N5O4 Molecular Weight (g/mol): 267.25 MDL Number: MFCD00150760 InChI Key: YKBGVTZYEHREMT-DWFKHXNSNA-N Synonym: 2'-deoxyguanosine,deoxyguanosine,guanine deoxyriboside,2-deoxyguanosine,guanosine, 2'-deoxy,guanine deoxy nucleoside,2'-deoxy-guanosine,2;-deoxyguanosine,unii-g9481n71ro,guanine, 9-2-deoxy-beta-d-erythro-pentofuranosyl PubChem CID: 187790 ChEBI: CHEBI:17172 IUPAC Name: 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one SMILES: NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1
2-Chloro-2'-arabino-fluoro-2'-deoxyadenosine, 99+%, Thermo Scientific Chemicals
CAS: 123318-82-1 Molecular Formula: C10H12ClN5O3 Molecular Weight (g/mol): 285.69 MDL Number: MFCD00871077 InChI Key: ADXUXRNLBYKGOA-GPGUAWMRNA-N Synonym: clofarabine,clolar,evoltra,clofarex,cafda,clofarabina,clofarabinum,clofarabine usan,cl-f-ara-a,c1-f-ara-a PubChem CID: 119182 ChEBI: CHEBI:681569 IUPAC Name: (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol SMILES: NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3Cl)C2=NC=N1
8-Bromo-2'-deoxyguanosine 98.0+%, TCI America™
CAS: 13389-03-2 Molecular Formula: C10H12BrN5O4 Molecular Weight (g/mol): 346.14 MDL Number: MFCD01630971 InChI Key: MKDXZFVCXWXGBQ-QXZWWJJYNA-N PubChem CID: 10947964 ChEBI: CHEBI:61072 IUPAC Name: 2-amino-8-bromo-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one SMILES: NC1=NC2=C(N=C(Br)N2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1